跳至主要内容
临床试验/NCT05759455
NCT05759455尚未招募不适用

Vitamen D in Autism

Assiut University0 个研究点目标入组 50 人开始时间: 2023年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
50
主要终点
Assessment of Vitamin D level in Children with Autism in assiut university children hospital

研究概览

简要总结

In the present study, we aim to evaluate the serum level of 25 hydrxy vitamin D in autistic children .

详细描述

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impaired social interaction and communication, repetitive and stereotyped behaviors, and restricted interests ( Lord et al,2018).

Autism is becoming increasingly common. Recently, the Centers for Disease Control and Prevention reported that the prevalence of autism among 8-year-old children in the United States in 2016 was 1/54, with a 4.3:1 ratio of males to females ( Maenner et al ,2020).

Autistic individuals manifest problematic behaviors, such as attacking, self-injury, resistance to orders, and failure of normal conversation, and are usually comorbid with social-anxiety, attention-deficit/hyperactivity, sleep-wake disorders, and obsessive-compulsive disorders. As such, it is difficult for them to obtain the same education levels as their neurotypical peers, find full-time jobs, or live independently ( Lord et al,2018),( Lai et al , 2019) .

Fortunately, evidence indicates that appropriate and early intervention could help autistic individuals improve their symptoms and life quality (Landa ., 2018).

Notably, research shows that nutritional and dietary intervention is an effective way to improve nutritional status, non-verbal IQ, and autism symptoms (Adams et al ,2018). Therefore, it is essential to identify physiological dysfunction and abnormal nutritional status in autistic individuals and then take corresponding interventions.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Prospective

入排标准

年龄范围
10 Months 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Patient who full filled the diagnostic criteria of autism spectrum disorder according to DSM-IV.

排除标准

  • Children using vitamin D supplement. 2)patients with associated congenital malformation. 3)patients with chromosomal abnormalities. 4)patients with chronic physical illness. 5)patients with epilepsy. 6)patients with hepatic or renal disease.

结局指标

主要结局

Assessment of Vitamin D level in Children with Autism in assiut university children hospital

时间窗: 2 years

In the present study, we aim to evaluate the serum level of 25 hydrxy vitamin D in autistic children .

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmed Abdelmoneim Ahmed

assiutU

Assiut University

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