Clinical Study on the Diagnostic and Predictive Value of MRI Multifunctional Imaging in Bladder Tumors
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 178
- 试验地点
- 1
- 主要终点
- quantitative parameters by MRI
研究概览
简要总结
This study prospectively included 178 patients with bladder neoplastic lesions who planned to undergo surgery (with or without preoperative neoadjuvant chemotherapy). Inclusion criteria: Patients with pathologically confirmed bladder cancer after radical or partial cystectomy or TURBT (< 2 weeks between surgical resection and imaging). Exclusion criteria: 1) Prior history of chemotherapy and/or radiotherapy; 2) No surgical resection; 3) The interval between surgical resection and imaging examination is > 2 weeks; 4) Obvious artifacts; 5)MRI scan contraindications. All subjects underwent pelvic MRI. Data was collected using a Siemens VIDA 3TMR scanner (Siemens Healthcare, Erlangen, Germany). All subjects underwent standardized scanning protocols. The obtained images are post-processed and the experimental results are analyzed statistically.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of bladder neoplasm
- •Must undergo radical or partial cystectomy or TURBT surgery within 2 weeks between surgical resection and imaging
排除标准
- •A history of pelvic radiotherapy or chemotherapy;
- •Lack of pathological findings or no surgery;
- •The interval between surgical resection and imaging examination > 2 weeks;
- •Poor image quality due to poor coordination or motion artifacts;
- •MRI scan contraindications
结局指标
主要结局
quantitative parameters by MRI
时间窗: From the time the participants completed the MRI scan to the post-processing of the resulting images,assessed up to 2 months
quantitative parameters by functional MRI
次要结局
未报告次要终点