Enabling Microbiomics- Driven Personalized Nutrition (EMPOWER)
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- Mayo Clinic
- 入组人数
- 4,001
- 试验地点
- 2
- 主要终点
- To Correlate Differences in Diet and Microbiome with Different GI Symptoms and Disease States
研究概览
简要总结
The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions.
The main question investigators aim to answer is:
Are host genetics, diet, and microbiome all important determinants of GI disorders, and how their relative contribution varies among individuals and populations.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age greater than or equal to 18 years
- •Gastrointestinal patients with or without genomic sequencing results available for the following cohorts:
- •Inflammatory Bowel Disease (IBD)
- •Irritable Bowel Syndrome (IBS)
- •Crohn's Disease
- •Celiac Disease
- •Constipation
- •Healthy age and sex matched controls with or without genomic sequencing results available
- •o Control is defined as patients without gastrointestinal disease or no symptoms at time of sampling
- •Able to provide written, informed consent
- •Participant has a smartphone device with access to internet connection
排除标准
- •Patients with cognitive impairment
- •Active use of antibiotics at the time of stool collection
结局指标
主要结局
To Correlate Differences in Diet and Microbiome with Different GI Symptoms and Disease States
时间窗: From enrollment through study completion, an average of 1 year.
Investigators will prospectively follow the clinical course of the patients throughout the duration of the study. Patient health outcomes will be documented from their medical record while the study is actively enrolling or undergoing data analysis.
次要结局
未报告次要终点
研究者
Purna C. Kashyap, MBBS
Principal Investigator
Mayo Clinic