The Need of Renal Replacement Therapy and In-Hospital Mortality Incidence In Patients With Cardiac Surgery Associated Acute Kidney Injury: Retrospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,113
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
The goal of this study is to analyse the relation of severe acute kidney injury post cardiac surgery which characterised by the need of renal replacement therapy, with in-hospital postoperative mortality incidence.
The main question it aims to answer:
To compare between patients complicated with acute kidney injury and exposure of renal replacement therapy (AKI-RRT) and patients complicated with acute kidney injury which does not require renal replacement therapy, in associated with in-hospital postoperative mortality.
详细描述
Type of study: observational study
Participant population: Post cardiac surgery patients with condition of acute kidney injury postoperative, will be assigned into 2 groups, based on their exposure to renal replacement therapy. Those groups are:
Group AKI-RRT : patients with AKI postoperative with exposure of renal replacement therapy Group AKI non RRT : patients with AKI postoperative, with no exposure to renal replacement therapy Researchers will compare group AKI-RRT and AKI non RRT to analyse the association to postoperative mortality, and other factors that related to mortality variable.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are at least 18 years old, underwent cardiac surgery in Harapan Kita National Cardiovascular Center from January 2020 to December
- •Patients with condition was complicated with Acute Kidney Injury (AKI) which was characterised by an increase in serum creatinine > 0.3 mg/dL or > 150% of the preoperative serum creatinine value, which was checked within 12 hours post-operative.
- •All patients' data is recorded in the medical records unit.
排除标准
- •Patients with previous history of dialysis or renal failure in dialysis.
- •Incomplete or loss of patients' data.
结局指标
主要结局
Mortality
时间窗: From ICU admission postoperative until the death date during hospital care, assessed up to 3 months
Number of participants who died of any cause during postoperative care in hospital
次要结局
- ICU Stay Over 5 Days(Time of ICU length of stay measured with days, up to 4 weeks)
- Mechanical Ventilation > 48 Hours(Time of ventilator usage measure with hours, up to 4 weeks)
研究者
Prieta Adriane MD
MD Anesthesiologist
National Cardiovascular Center Harapan Kita Hospital Indonesia