Acid-inhibitory effects of vonoprazan compared with rabeprazole in healthy adult subjects - a randomised open-label cross-over study - Acid-inhibitory effects of vonoprazan compared with rabeprazole in healthy adult subjects - a randomised open-label cross-over study

Osaka medical collage0 个研究点目标入组 30 人开始时间: 2016年6月1日最近更新: 2023年10月17日

适应症

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•1) by constriction or deformation of the upper gastrointestinal tract, drug administration and the endoscope insertion difficult. 2) there is a history of acid-related diseases. 3) there is a surgical history. 4) there is a history of radiation therapy to the upper abdomen. 5) serious complications(with heart failure, kidney failure, liver failure, respiratory failure). 6) Experience of oral administration of Vonoprazan or Rabeprazole. 7) there is a history of medication to up to one month before the registration date. 8) there is a history eradication of Helicobacter pylori. 9) Helicobacter pylori test positive (anti-HP IgG antibody, urease test, any one is positive urea breath test). 10) There is activity malignant tumor patients and other serious systemic complication. 11) there are abnormal findings in the upper gastrointestinal endoscopy. 12) F scale positive (total score 8 points or more) 13) There is a history of allergy to test drugs 14) pregnancy and lactation. 15) there is a plan of treatment with respect to the upper gastrointestinal tract disease. 16) there is a registration history in the study. 17) can not be obtained the consent to participate in this clinical study. 18) the study director (sharing) who doctor has determined to be inappropriate as a subject.

发起方

Osaka medical collage