The Effect of Post-voiding Reisdual Urine on Non-muscle Invasive Bladder Cancer Recurrence and Progression
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 500
- 试验地点
- 6
- 主要终点
- Recurrence
研究概览
简要总结
Although transurethral resection is the main treatment option for stage Ta and T1 disease, relapse is frequently detected. Tumor number, tumor size, T stage, presence of in situ carcinoma and tumor grade are risk factors for recurrence. The relationship between post voiding residual urine volume and bladder tumor recurrence and progression has not been clearly established. The investigators aimed to examine the effect of high post voiding residual urine volume on recurrence and progression based on the hypothesis that tumor cells circulating in the bladder may increase with excess residual urine.
详细描述
Although transurethral resection is the main treatment option for stage Ta and T1 disease, relapse is frequently detected. Tumor number, tumor size, T stage, presence of in situ carcinoma and tumor grade are risk factors for recurrence. The relationship between post voiding residual urine volume and bladder tumor recurrence and progression has not been clearly established. Participants who underwent transurethral resection for bladder tumor will be included in the study. The investigators aimed to examine the effect of high post voiding residual urine volume on recurrence and progression based on the hypothesis that tumor cells circulating in the bladder may increase with excess residual urine.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with transitional cell non-muscle invasive bladder cancer (NMIBC) pathology
- •Patients with a diagnosis of Bladder cancer (NMIBC)
- •Patients undergoing transurethral resection for bladder cancer (NMIBC)
- •≥18 years old patients
排除标准
- •Non-transitional cell bladder cancers
- •Patients with muscle-invasive bladder cancer pathology
- •<18 years old patients
研究组 & 干预措施
Low residual volume
Bladder tumor patients with low residual volume
High residual volume
Bladder tumor patients with high residual volume
结局指标
主要结局
Recurrence
时间窗: 1 year
Non-muscle invasive bladder cancer recurrence rate
次要结局
- Progression(1 year)
研究者
Mehmet Caglar Cakici
Department of Urology
Istanbul Medeniyet University