Page 1/27 Effectiveness of an Expert-Guided Early Tracheostomy Pathway for Mechanically Ventilated Critically Ill Adults in Jordan
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 104
- 试验地点
- 1
- 主要终点
- Duration of hospitalization from admission to ventilator independent discharge
研究概览
简要总结
The optimal timing of tracheostomy insertion remains uncertain. We hypothesized that a clinical pathway including expert-informed risk assessment regarding predicted duration of mechanical (MV) would enhance the effectiveness of early percutaneous dilatational tracheostomy (PDT) for patients with anticipated prolonged durations of MV, as reflected by duration of ventilation, complications, and patient-centered outcomes.
详细描述
three-year prospective observational study (2018-2020) at a tertiary care level 1 trauma center (King Hussein Medical Center) in Amman Jordan and 4 affiliated subspecialty hospitals. The study sequentially enrolled all adult patients (>18yo) with critical illness receiving MV in an intensive care unit for 48 hours or longer. Institutional ethical committee clearance for the study was secured.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing continued MV for 48 or more hours for whom continuation of life-prolonging therapy was indicated
排除标准
- •Patients at imminent risk of death were included
研究组 & 干预措施
Early Percutaneous dilatational tracheostomy
PDT reccomended for patients with high risk for prolonged mechanical ventilation.
干预措施: Expert-Guided Early Tracheostomy (Other)
结局指标
主要结局
Duration of hospitalization from admission to ventilator independent discharge
时间窗: Hospital stay up to 90 days
Length of stay in days
次要结局
- Days of ventilation requiring administration of NMB(Hospital stay up to 90 days)
- Difference in average and total morphine equivalent dose(Hospital stay up to 90 days)
- 90 day survival(90 days)
- Easy or Moderately Easy to Wean(Hospital stay up to 90 days)
研究者
Ivor Douglas
Professor
Denver Health and Hospital Authority