NCT07240051已完成不适用
Assessment of the Efficacy and Safety of 50% Glycolic Acid, 30% Salicylic Acid, and Modified Jessner's Chemical Peels in the Treatment of Active Acne and Post-acne Hyperpigmentation: Randomized Controlled Trial
Nahla Maher Mahmoud Mahran1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2024年3月9日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- improvement in acne vulgaris by assessing Global acne scoring system and post-acne hyperpigmentation index
研究概览
简要总结
Assessment of the Efficacy and Safety of 50% Glycolic Acid, 30% Salicylic Acid, and Modified Jessner's Chemical Peels in the Treatment of Active Acne and Post-acne Hyperpigmentation: Randomized Controlled Trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- — 至 65 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Facial active acne (mild and moderate cases)
- •post-acne hyperpigmentation
- •a minimum age of 18 years
- •skin phototype III or IV
排除标准
- •Pregnant or nursing women
- •active infection in the treatment area (e.g., verrucae and herpes simplex)
- •systemic disease (hypertension, diabetes, or bleeding tendency)
- •systemic retinoid or laser treatment within the last 6 months
- •history of keloidal tendency or Aspirin sensitivity.
研究组 & 干预措施
glycolic acid group
Active Comparator
30 patients received 50% glycolic acid peels
干预措施: Glycolic acid peel alone (Procedure)
Modified Jessener group
Active Comparator
30 patients received MJ peel
干预措施: modified jessener (Procedure)
Salicylic acid group
Active Comparator
30 patients received Salicylic acid 30%
干预措施: salicylic acid (Procedure)
结局指标
主要结局
improvement in acne vulgaris by assessing Global acne scoring system and post-acne hyperpigmentation index
时间窗: 6 months
次要结局
未报告次要终点
研究者
Nahla Maher Mahmoud Mahran
lecturer of Dermatology
Cairo University
研究点 (1)
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