Opioid Free Anaesthesia in Cardiac Surgery With Cardiopulmonary Bypas
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,772
- 试验地点
- 1
- 主要终点
- ICU stays (days)
研究概览
简要总结
Since the 90's the concept of morphine sparing and morphine free anaesthesia (OFA) has progressively developed in non-cardiac surgery. The principle is based on the fact that in a sleeping patient a sympathetic reaction marked by hemodynamic modifications does not translate into a painful phenomenon, that a painful phenomenon in a sleeping patient is not memorized, that hormonal stress, the sympathetic reaction and the inflammatory reaction can be controlled by other therapeutic classes than a morphine agent. This therapeutic management would avoid the side effects associated with the use of morphine. In this hypothesis, OFA is more and more practiced in various situations without the real impact in terms of clinical benefit being clearly demonstrated. In cardiac surgery, some centers practice OFA with various protocols.The purpose of this work is to retrospectively evaluate over a defined period the incidence of postoperative complications, length of stay in the ICU/hospital, and death rate between patients managed with/without OFA based on lidocaine.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age over 18 years Cardiac surgery with cardiopulmonary bypass performed between January 2019 and June 2021
排除标准
- •LVAD Heart transplantation Incomplete data in relation to outcomes
研究组 & 干预措施
Opioid free anaesthesia
patient anesthtesized with lidocaine
干预措施: Data collection (Other)
Opioid anaesthesia
patients anesthetized with sufentanil
干预措施: Data collection (Other)
结局指标
主要结局
ICU stays (days)
时间窗: Day 30
Total stay in ICU in day
次要结局
- Hospital stays (days)(Day 30)
- Complications(Day 30)
