U/s Guided Oblique Subcostal Transversus Abdominis Plane Block Versus Erector Spinae Plane Block as Pre-emptive Analgesia for Open Umbilical Hernia Repair; Randomized, Double-blinded Controlled Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- total morphine consumption.
研究概览
简要总结
Administration of opioids for the treatment of acute pain after open umbilical hernia repair is associated with many side effects. Erector spinae plane (ESP) block is a novel inter-fascial plane block used in postoperative pain and chronic neuropathic pain relief of the thoracoabdominal region.TAP block is a regional injection of local anaesthetic between the transversus abdominis and internal oblique muscle planes. TAP block affects the sensory nerves of the anterolateral abdominal wall (T6-L1) that innervate the abdomen.
详细描述
TAP block is a regional injection of local anaesthetic between the transversus abdominis and internal oblique muscle planes. TAP block affects the sensory nerves of the anterolateral abdominal wall (T6-L1) that innervate the abdomen. TAP block is an easy technique and decreases postoperative pain and opioid consumption.
Erector spinae plane (ESP) block is a novel inter-fascial plane block used in postoperative pain and chronic neuropathic pain relief of the thoracoabdominal region. However, its first use was for the treatment of chronic pain, but recently it has been used as a postoperative regional analgesia technique in different surgeries from the shoulder to hip regions (3-4) The present study will be carried out to compare the preemptive analgesic efficacy between the ultrasound-guided bilateral ESP block versus bilateral oblique subcostal TAP block on patients undergoing open umbilical hernia repair.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
盲法说明
Double-blinded
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •American Society of anesthesiologists I-II, scheduled for open umbilical hernia repair.
- •Age range of 18-65 years.
排除标准
- •patient refusal.
- •Patients belonging to ASA grade III and grade IV.
- •Extreme obesity (BMI >35).
- •hepatic or renal insufficiency.
- •preoperative cognitive dysfunction or communication disorder.
- •allergy to amide-type local anaesthetics.
- •back puncture site infection.
- •Coagulation disorders, pregnancy, drug abusers.
研究组 & 干预措施
Group (T)
receive preoperative bilateral ultrasound-guided oblique subcostal transversus abdominis plane block.
干预措施: Bupivacain (Drug)
Group (T)
receive preoperative bilateral ultrasound-guided oblique subcostal transversus abdominis plane block.
干预措施: Bupivacaine (Drug)
Group (E)
receive preoperative bilateral ultrasound-guided erector spinae plane block.
干预措施: Bupivacain (Drug)
Group (E)
receive preoperative bilateral ultrasound-guided erector spinae plane block.
干预措施: Bupivacaine (Drug)
结局指标
主要结局
total morphine consumption.
时间窗: in first 24 hours
Amount of morphine used as rescue analgesia post-operatively.
次要结局
- time of first analgesic request(in 24 hours)
- pain severity evaluation.(at PACU admission , 30 minutes , 2 hours , 4 hours , 8 hours ,12 hours ,18 hours and 24 hours post operative)
- Intraoperative fentanyl consumption(From the start of operation till its end up to 3 hours.)
研究者
Fatma Ahmed Abdel Fatah
Lecturer
Benha University