Assesment of the Metabolomic Signature in COVID-19 Patients (SignCov Study)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- Identifying the metabolomic signature
研究概览
简要总结
Metabolomics is the analysis of small molecules in a biological sample (cells, tissues or biological fluids). It can potentially detect very sensitively any change related to a pathology or exposure to a toxic agent. The analyses are fast, inexpensive and therefore applicable in routine, particularly in health care. Given the emergence of this new disease, COVID-19, there is a real need to better understand the pathophysiological mechanisms of SARS-CoV-2 infection. In this context, metabolomics could have a place and could lead to the development of interesting diagnostic or prognostic tools. The objective of this study is to identify, through the analysis of biological samples (blood and urine), whether there is a metabolomic signature in patients with COVID-19.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient over 18 years of age
- •affiliated to a social security scheme
- •consultant in the emergency department and/or being hospitalized for suspected SARS CoV infection
- •confirmation, after medical examination, of the need for a biological examination (this will negate the need for additional venipuncture)
- •Exclusion criteria:
- •Patient who do not meet inclusion criteria
- •Person subject to a guardianship order
- •Opposition to the use of the data or samples (withdrawal of non-opposition) / Sponsor's or investigator's decision
排除标准
- 未提供
结局指标
主要结局
Identifying the metabolomic signature
时间窗: Enrollment
To dentified a metabolomic profile using liquid chromatography combined with mass spectrometry (LC-MS) on the serum and urine of COVID-19 patients
次要结局
- Identification of the metabolomic profile according to clinical severity.(Enrollment)