Changes in Outcomes of Treatment for Adolescent Anorexia Nervosa After Implementation of Family Based Treatment in a Norwegian Child and Adolescent Mental Health Service: A Retrospective Cohort Study With Prospective Follow-up
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 175
- 试验地点
- 1
- 主要终点
- Time to weight restoration
研究概览
简要总结
The goal of this observational study is to compare short and long-term effects of manualised Family Based Treatment for adolescent anorexia nervosa to those of non-manualised family therapy. The study will approach former patients who were treated before and after Family Based Therapy was adopted in an outpatient clinic, and extract data from electronic health records and public registries.
详细描述
A two-group retrospective exploratory cohort study with longitudinal follow-up comparing adolescents with anorexia nervosa treated with generic family therapy to those treated with the manualised Family Based Treatment (FBT). The primary aim is to investigate whether adoption of FBT has led to faster normalisation of weight and lower rates of eating disorder in early adulthood. Secondary aims are to investigate whether implementation of FBT has changed the time to discharge, heterogeneity of patient weight change across treatment, rates of adverse events, rates of readmission, patient experiences of the treatment, long term functional outcomes and mortality. Data are extracted from patient health records, reported by participants and extracted from public registries.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of F50.0 Anorexia nervosa or F50.1 Atypical anorexia nervosa according to the International Classification of Diseases-10.
排除标准
- •Patient was treated during the years 2018-2020 and FBT was never initiated according to patient health records.
结局指标
主要结局
Time to weight restoration
时间窗: Assessed retrospectively at enrolment.
Number of days from start of treatment to a weight measurement placing the patient at or above 95% of expected body weight (50. percentile) for age and sex given Norwegian population norms.
次要结局
- Time to discharge from treatment(Assessed retrospectively at enrolment.)
- Treatment for eating disorder in adulthood(Assessed 5, 10, 15 and 20 years post treatment.)
- Mortality(Assessed 5, 10, 15 and 20 years post treatment.)
- Employment status and welfare benefits(Assessed 5, 10, 15 and 20 years post treatment.)
- Time to readmission to treatment(Assessed retrospectively at enrolment.)
- Level of education(Assessed 5, 10, 15 and 20 years post treatment.)
研究者
Erling W. Rognli
Psykologspesialist
University Hospital, Akershus