Efficacy and safety of posterior leaflet extension with glutaraldehyde-treated autologous pericardial patch for atrial mitral regurgitation

Sakamoto Hiroaki0 个研究点目标入组 10 人开始时间: 2021年4月7日最近更新: 2023年10月17日

试验速览

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•1) Patients with atrial MR of moderate (grade 2) or greater
•2) Patients with heart failure symptoms of NYHA functional classification II or higher due to significant atrial MR even after optimal medications and have indication of surgery
•3) Men and women over 20 years old
•4) Patients with written informed consent

•1) Patients with the following findings unsuitable for reconstrucion of mitral valve with autologous pericardial patch
•1. Moderate or greater mitral valve stenosis
•2. Severe mitral valve calcification
•3. Severe pericardial calcification
•2) Patients with severe left ventricular dysfunction (left ventricular ejection fraction <30%)
•3) Patients with infections endocarditis
•4) Patients with acute myocardial infarction within 30 days before surgery
•5) Patients with severe lung disease (emphysema, chronic obstructive pulmonary disease, pulmonary fibrosis)
•6) Patients with severe liver cirrhosis
•7) Patients with a history of pericarditis
•8) Women who are pregnant or may become pregnant
•9) Patients who are judged inappropriate by the researcher

发起方

Sakamoto Hiroaki