Immature Myeloid Cells in Respiratory Syncytial Virus Bronchioliltis
试验速览
- 阶段
- 不适用
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- Number of Immature Myeloid Cells in Respiratory Secretions
研究概览
简要总结
The investigators hypothesize that Respiratory Syncytial Virus (RSV) infection may influence the population of lung immature myeloid cells and dendritic cells in a way that will impair their ability to invoke an effective immune response and lead to prolonged inflammation, angiogenesis and scarring. This may lead in turn to disturbed lung function.
Our aim is to determine the presence and phenotype of immature myeloid cells present in respiratory secretions of children with RSV bronchiolitis as compared to non-RSV bronchiolitis and healthy controls.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 2 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Bronchiolitis
排除标准
- •Chronic disease
结局指标
主要结局
Number of Immature Myeloid Cells in Respiratory Secretions
时间窗: Participants will be followed for the duration of hospital stay, an expected average of one week
Respiratory secretions obtained from child presenting with bronchiolitis will be examined for the presence of immature myeloid cells
次要结局
未报告次要终点