Efficacy of Application of Myriad Matrix to Split Thickness Skin Graft Sites
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 入组人数
- 30
- 主要终点
- Pain Improvement
研究概览
简要总结
To determine if application of Myriad Matrix to split thickness skin graft donor sites improves post-operative pain and appearance of the wound.
详细描述
In the head and neck practice at UAB, split thickness skin grafts are a commonly used procedure for simple reconstruction. The standard dressing for donor sites is a strip of vaseline gauze which remains on the site the wound dries, and the gauze eventually falls off. Post operative pain and poor wound healing is a well established complication of the donor site, and various methods have been studied in an attempt to reduce these complications for patients in the post operative period. (1, 2, 3)
Myriad matrix is an engineered extracellular matrix (Ovine Forestomach Matrix) used for soft issue repair in complex wounds. This has been sporadically used by some of the faculty members at UAB for split thickness skin graft donor site dressings with anectodal improvement in pain and healing, though this has not yet been studied to our knowledge.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients 18 and over who are undergoing a split thickness skin graft at UAB.
排除标准
- •Patients who are not planned to undergo a split thickness skin graft or who are unable or do not plan to attend follow up appointments will not be included.
结局指标
主要结局
Pain Improvement
时间窗: 48 hours, 2 weeks, 4-6 weeks post operative visit
patients will rate pain level at donor site
Wound Healing
时间窗: 2 weeks and 4-6 weeks post operative visit
Patients will rate appearance of would using the scar-Q questionnaire
次要结局
未报告次要终点
研究者
Benjamin Greene
Associate Professor
University of Alabama at Birmingham