Correlation Between Angle Closure Glaucoma Data and Lens Zonule Status
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 263
- 试验地点
- 1
- 主要终点
- Axial Length (AL), Lens Thickness (LT),Lens Vault (LV), Pupil Diameter (PD),
研究概览
简要总结
The goal of this observational study is to discuss the correlation between primary angle-closure glaucoma and the state of the suspended ligament of the lens and the pathogenesis of PACG by measuring the biological data of primary angle-closure glaucoma and observing its anatomical changes.
详细描述
Patients clinically diagnosed with Primary angle-closure glaucoma (PACG) and normal control patients from December 2020 to January 2022 were enrolled in this study.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 47 Years 至 91 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The depth of the anterior chamber is normal, and the whole corner of the chamber is open;
- •The cup-to-plate ratio is less than 0.5;
- •No family history of glaucoma.
排除标准
- •Previous history of trauma or internal eye surgery in both eyes or one eye;
- •Used "pilocarpine", "atropine" and other drugs to change the size of the pupil and the shape of the chamber Angle within 1 week;
- •Combined with other eye diseases affecting the Angle and suspension ligament, such as uveitis, ciliary cyst, high myopia, retinal diseases, etc.;
- •Can not cooperate with UBM and Angle scopy;
- •Refuse to participate in this researcher.
结局指标
主要结局
Axial Length (AL), Lens Thickness (LT),Lens Vault (LV), Pupil Diameter (PD),
时间窗: before operation
Axial Length (AL), Lens Thickness (LT),Lens Vault (LV), Pupil Diameter (PD),
Anterior Chamber Depth (ACD) in seat and rectum position, White To White (WTW), pupil vault (LV), pupil diameter (PD), The Lens Zonular Length (LZL) and Angle Opening Distance at 500μm (AOD500) in the upper, lower, nasal and temporal directions
时间窗: before operation
Anterior Chamber Depth (ACD) in seat and rectum position, White To White (WTW), pupil vault (LV), pupil diameter (PD), The Lens Zonular Length (LZL) and Angle Opening Distance at 500μm (AOD500) in the upper, lower, nasal and temporal directions
次要结局
未报告次要终点
研究者
Guangfu Dang
professor
Qianfoshan Hospital