NCT07434635招募中4 期
APPRAISE: Assessment of Pain and Posterior Synechiae Reduction With Atropine, an Investigation of Post-Surgical Eyes
干预措施
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 62
- 试验地点
- 1
- 主要终点
- Pain score on the Visual Analog Scale (VAS)
研究概览
简要总结
The study will evaluate whether atropine eyedrops are beneficial when used after certain eye surgeries.
详细描述
Atropine eyedrops are often used after certain eye surgeries. This study will compare several outcomes following surgery in patients either using or not using this treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient undergoing vitrectomy surgery
- •able to give informed consent
排除标准
- •post-operative eyedrop regimens that include topical non steroidal anti-inflammatory medications
- •subjects with altered post-operative eyedrop schedule for enhanced inflammation control
- •documented allergy to atropine
研究组 & 干预措施
Control
No Intervention
No atropine
Experimental
Experimental
Participant uses atropine eyedrops
干预措施: Atropine 1% (Drug)
结局指标
主要结局
Pain score on the Visual Analog Scale (VAS)
时间窗: 1 month
Whether atropine use impacts post-operative pain score on the standard Visual Analog Scale (VAS)
次要结局
- Anterior chamber inflammation (aqueous cell and flare)(1 month)
- Cystoid macular edema detected by optical coherence tomography(1 month)
- Time to visual recovery(1 month)
- Intraocular pressure(1 month)
- Posterior synechiae formation(1 month)
研究者
研究点 (1)
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