ACTRN12620000890932招募中未知
Does repetitive transcranial magnetic stimulation (rTMS), compared to sham rTMS, improve social communication in adolescents and young adults with autism spectrum disorder (ASD)?
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 14 Years 至 40 Years（—）
- 性别
- All
入选标准
- •Aged between14-40 years
- •Diagnosed with autism spectrum disorder (ASD) based on DSM-5 criteria, and confirmed via Autism Diagnostic Observation Schedule – Second Edition (ADOS-2)
排除标准
- •History of seizure/s or epilepsy
- •History of serious head injury
- •Contraindication to magnetic resonance imaging (MRI)
- •Formal verbal intelligence quotient VIQ assessment <55, as determined by Wechsler Abbreviated Scale of Intelligence (WASI-2) or another standardised cognitive assessment
- •Comorbid neurological or psychiatric diagnosis not commonly associated with ASD (e.g., psychosis)
- •Unstable medical condition
- •Unstable medication regime, or medication contraindicated for TMS
- •Substance use/abuse disorder
- •Concurrent treatment targeting social communication
- •Evidence of significant epileptiform activity on EEG (e.g., seizures on EEG, runs of epileptiform discharges)
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