ITMCTR1900002799尚未招募未知
The investigation for the effects of Ti-Luo Hua-Yu Yang-Xue Ming-Mu method on the eyeground blood flow of the NTG patients
China Academy of Chinese Medical Sciences Eye Hospital0 个研究点开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 20 至 75（—）
- 性别
- All
入选标准
- •Part one inclusion criteria:
- •Inclusion criteria for Normal control group:
- •1. the best corrected visual acuity (BCVA) > 0.8;
- •2. IOP <21 mmHg;
- •3. The eyeground is normal, C/D is normal. OCT shows normal RNFL thickness and normal visual field;
- •4. Aged 20 and 75 years.
- •Inclusion criteria for HTG group:
- •1. meet the diagnostic criteria;
- •2. Aged between 20 and 75 years;
- •Inclusion criteria of NTG group:
- •1. meet the diagnostic criteria and the TCM Syndrome Diagnostic Criteria;
- •2. Ages between 20 and 75 years;
- •3. After lowering intraocular pressure drug therapy, intraocular pressure stabilized below 15mmHg for more than 2 months.
- •Part two inclusion criteria:
- •1. meet the diagnostic criteria and the TCM Syndrome Diagnostic Criteria;
- •2. Ages between 20 and 75 years;
- •3. After lowering intraocular pressure drug therapy, intraocular pressure stabilized below 15mmHg for more than 2 months.
排除标准
- •Part one exclusion criteria:
- •Exclusion criteria for control group:
- •1. family history of glaucoma;
- •2. diopter greater than + 3.00d or less than -8.00d;
- •3. patients with serious systemic diseases such as heart failure, liver and kidney dysfunctions, gastric and duodenal ulcers, diabetes mellitus and malignant hypertension. Serum creatinine > 2 times upper limit of normal value (ULN); Serum glutamine transaminase > 3 times ULN;
- •4. History of eye surgery or trauma;
- •5. Mental illness or anxiety, depression and other abnormal psychological state and malignant tumors;
- •6. Pregnant or nursing women;
- •7. Failing to follow doctor's advice and cooperate with relevant examinations.
- •Exclusion criteria for NTG and HTG group:
- •1. Fixation loss > 20%;
- •2. Diopter between + 3.00d and -8.00d;
- •3. The false-positive or false-negative rate of visual field tested by Humphrey is greater than 33;
- •4. Patients with malignant tumors;
- •5. History of eye surgery or trauma;
- •6. In the past 1 month, have used traditional Chinese medicine or western medicine of vasodilator and neuroprotective drugs;
- •7. Suspicious or definite allergy to the study drug;
- •8. Serum creatinine > 2 ULN;
- •9. Serum glutamine transaminase > 3 ULN;
- •10. History of eye surgery or trauma;
- •11. Patients with heart Yang deficiency syndrome are mainly manifested by chest tightness and chest pain, palpitations and cold sweat, and aversion to cold limbs;
- •12. Mental illness or anxiety, depression and other abnormal psychological state and malignant tumors;
- •13. Participated in other clinical trials in the last 3 months;
- •14. Pregnant or nursing women;
- •15. Failing to follow doctor's advice and cooperate with relevant examinations.
- •Part two exclusion criteria:
- •Exclusion criteria for NTG and HTG group:
- •1. Fixation loss > 20%;
- •2. Diopter between + 3.00d and -8.00d;
- •3. The false-positive or false-negative rate of visual field tested by Humphrey is greater than 33;
- •4. Patients with malignant tumors;
- •5. History of eye surgery or trauma;
- •6. In the past 1 month, have used traditional Chinese medicine or western medicine of vasodilator and neuroprotective drugs;
- •7. Suspicious or definite allergy to the study drug;
- •8. Serum creatinine > 2 ULN;
- •9. Serum glutamine transaminase > 3 ULN;
- •10. History of eye surgery or trauma;
- •11. Patients with heart Yang deficiency syndrome are mainly manifested by chest tightness and chest pain, palpitations and cold sweat, and aversion to cold limbs;
- •12. Mental illness or anxiety, depression and other abnormal psychological state and malignant tumors;
- •13. Participated in other clinical trials in the last 3 months;
- •14. Pregnant or nursing women;
- •15. Failing to follow doctor's advice and cooperate with relevant examinations.
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