RBR-5p6nv8b尚未招募未知
Grape seed flour Supplementation as a strategy to reverse muscle mass loss in perioperative colorectal cancer Cachexia patients: a translational study
niversidade Federal de São Paulo0 个研究点开始时间: 2023年2月7日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Intervention
入排标准
- 年龄范围
- 40Y 至 90Y（—）
入选标准
- •Histopathological diagnosis of colorectal carcinoma; Indication of curative surgery for resection of malignant primary colorectal tumor; Tumor classification according to the Union for Internacional Cancer Control (UICC) criteria; Pre-cachexia or cachexia diagnosis (2011 Consensus); Age between 40 and 90 years; Signed Informed Consent;
排除标准
- •Confirmed distant metastasis; Radio/Chemotherapy treatment in the last 3 months; Body Mass Index (BMI) greater than 40 kg/m²; History of liver function impairment (Child-Pugh-Turcotte score B and C); History of chronic kidney disease (defined according KDIGO 2012); HIV positive with AIDS-related complications; Hypersensitivity to trial supplement; Continuous supplementation of polyphenols or pre/probiotics in the last 3 months; Inflammatory bowel diseases (IBD) or chronic inflammatory processes unrelated to cachexia, such as autoimmune disorders; Pregnancy or breastfeeding.
研究者
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