influence of preload on repolarization (iPORT) - iPORT (influence of preload on repolarization)

Academisch Medisch Centrum0 个研究点目标入组 35 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

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•In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•* *18 years of age
•* Structural normal heart based on present clinical information (echocardiography, electrocardiogram)
•* Indication for an electrophysiological procedure based on a narrow complex tachycardia (presumed);
•o Concealed bypass
•o Atrioventricular node re-entry tachycardia (AVNRT)
•o Ectopic atrial tachycardia

•A potential subject who meets any of the following criteria will be excluded from participation in this study:;* Use of anti-arrhythmic medication
•* Atrial fibrillation at time of the stimulation protocol.
•* Any possibility of electrical remodelling of the ventricle;
•o The presence of an antidrome circle tachycardia; Wolf Parkinsson White syndrome (as due to the pre-excitation of the ventricles over the bypass some ventricular electrical remodelling can be expected).
•o History of persistent atrial fibrillation (AF); due to persistent AF the ventricles are stimulated irregularly and aberrant conduction could induce electrical remodelling of the ventricle.
•o History of frequent ventricular extrasystoli.;Exclusion criteria after informed consent is signed;
•o At time of the electrophysiological procedure an on-going narrow complex tachycardia (as this will intervene with the stimulation protocol and will make the ecg*s unsuitable for STV QT analysis).
•o During the stimulation protocol a large number of ventricular extra systoles (*5) or any other reason making the ecg*s unsuitable for STV QT analysis (e.g. movement artefacts)

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