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eurobiological correlates and mechanisms of the augmentation of psychotherapy with endurance exercise in mild to moderate depression - SPeED

Department Sport- und Gesundheitswissenschaften, Sozial- und Präventivmedizin, Universität Potsdam0 个研究点目标入组 105 人开始时间: 2015年7月28日最近更新: 2024年8月19日

适应症

试验速览

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•The study is conducted with 18- to 65- years old, as physical healthy diagnosed ambulant psychotherapy patients with the main diagnosis of a mild to moderate depressive episode diagnosed according to ICD-10 (F32.0, F32.1), which can also occur in the context of a recurrent depressive disorder (F33.0, F33.1). The presence of a major depressive episode is assured by creating structured clinical interview I for DSM - IV (SCID I) ; Axis I: mental disorders, depression section.
•The healthy control group (18-65 years old).
•Subjects of the healthy control group are 18-65 years old and have no major depressive disorder.

•Following exclusion criteria are applied: current severe depressive episode with and without psychotic symptoms (F32.2, F32.3, F33.2 or F33.3), current borderline or dissocial personality disorder, acute suicide risk, current or lifetime schizophrenia spectrum disorder, delusional disorders (F2x.x), bipolar affective disorder (F31.x), current dependence (alcohol, heroin, amphetamine, cocaine), minimum period of rest 12 month, current severe neurological diseases and illnesses of central nervous system, severe chronic obstructive pulmonary disease (COPD), coronary heart disease, cardiac insufficiency, anaemia, body mass index > 35 or < 18, language problems, non-correctable hearing and visual impairments, MRI unsuitability, current use of benzodiazepines or beta blockers within the last 7 days, tricyclic antidepressants with a dose of > 50mg per day, neuroleptics with a dose of > 30% of the maximum daily dose, regular endurance training (more than two times per week for 45min).

发起方

Department Sport- und Gesundheitswissenschaften, Sozial- und Präventivmedizin, Universität Potsdam