NCT06921239招募中不适用
HLA Antibodies in Systemic Lupus Erythematosus
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- prevalence of unexplained antibody positivity
研究概览
简要总结
Patients suffering from autoimmune diseases show false-positive results when anti-HLA antibodies are identified. This false positivity makes it difficult to obtain an organ transplant based on immunological compatibility (absence of anti-HLA antibodies directed against graft antigens). The objectives of this project are to study the prevalence of these false positivities in a population of lupus patients, and to evaluate biological tests that can negate these false positivities.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients Adults
- •Followed in the internal medicine department of Amiens University Hospital - With systemic lupus erythematosus
- •Without HLA immunization risk factors (no history of pregnancy, transfusions or transplants)
- •With sera stored in the biobank
排除标准
- •minor Patients
- •Opposing the re-use of their personal data for research purposes
结局指标
主要结局
prevalence of unexplained antibody positivity
时间窗: 6 months
prevalence of unexplained antibody positivity
次要结局
未报告次要终点
研究者
研究点 (1)
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