DRKS00031628进行中（未招募）4 期
Clinical application of a porcine hydroxyapatite (The Graft) and an alloplastic ß-Tricalciumphosphate (Osopia) in comparison to a bovine hydroxyapatite (BioOss) for maxillary sinus augmentation: a radiological and histological analysis - Maxillary sinus augmentation using porcine, bovine and alloplastic BSM
Mund-, Kiefer- und Gesichtschirurgische Klinik des Universitätsklinikums Erlangen0 个研究点目标入组 29 人开始时间: 2023年4月6日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 29
研究概览
简要总结
Histological analysis: DPBM acts as an osteoconductive bone substitute material with a rate for newly formed bone comparable to DBBM 4 months after maxillary sinus augmentation. Within the testing groups microstructured BCP showed a higher proportion of NFB, whereby compared to the control and testing groups no statistaical significant differences exists. Radiological analysis: Concerning bone graft stability/ volume DBBM and DPBM show comparable outcomes. Due to resorption, BCP showed inferior bone graft volume after healing (statistically significant) compared to DBBM and DPBM.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •edentulous upper jaw or residual dentition in the upper jaw posterior region
- •- insufficient bone supply in height and width
- •- remaining bone height in the maxillary alveolar crest between 4 and 6 mm
排除标准
- •- Acute infections
- •- Acute sinusitis
- •- Radiotherapy in the head and/or neck area
- •- Chemotherapy
- •- Poor oral hygiene or motivation
- •- Active periodontitis
- •- Pregnancy
- •- Drug or alcohol abuse
- •- Smoker (>10 p.d.)
- •- Hematological diseases
- •-Metabolic
- •- Uncontrolled or treatment-resistant diabetes
- •- Autoimmune diseases
- •- Immunological diseases
- •- Chronic osteopathies
- •- Antiresorptive medication (bisphosphonates, anti-RANKL antibodies, anti-VEGF antibodies, tyrosine kinase inhibitor, mTOR inhibitor)
- •- Steroid medication
- •- Untreated carious lesions of neighboring teeth
- •- Untreated endodontic lesions of neighboring teeth
- •- Limited mental abilities and language skills, so that study information and instructions cannot be understood
研究者
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