International COVID19 Clinical Evaluation Registry: HOPECOVID19. (Health Outcome Predictive Evaluation for COVID19)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 8,168
- 试验地点
- 1
- 主要终点
- Death
研究概览
简要总结
The investigators propose to select all COVID 19 patients attended in any health center (with in hospital beds), who have been discharged or have died at the time of the evaluation.
The main objective of the present study is to carefully characterize the clinical profile of patients infected with COVID-19 in order to develop a simple prognostic clinical score allowing, in selected cases, rapid logistic decision making (discharge with follow-up, referral to provisional/field hospitals or admission to more complex hospital centers).
As secondary objectives, the analysis of the risk-adjusted influence of treatments and previous comorbidities of patients infected with the disease will be performed.
详细描述
INTRODUCTION. The disease caused by the new respiratory virus (coronavirus) designated as SARS-CoV-2 has recently been classified as a pandemic by the WHO.
With an increasing number of confirmed cases in most countries worldwide, it is responsible for a significant morbidity and mortality and has motivated the implementation of measures at national and international levels with a great impact on the way of life of people throughout the whole planet.
In addition, this condition currently threatens many countries with the collapse of health systems, producing serious logistical problems due to extensive affectation of the population, which can worsen the prognosis of those primarily affected by COVID 19 and other patients with different pathologies and who may have difficulties to get healthcare.
Limited clinical information is available and generally limited to the Asian population, since the first cases were identified in Wuhan (Hubei, China).
PURPOSE. The main objective of the present study is to carefully characterize the clinical profile of patients infected with COVID-19 in order to develop a simple prognostic clinical score allowing, in selected cases, rapid logistic decision making (discharge with follow-up, referral to provisional/field hospitals or admission to more complex hospital centers).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients discharged (deceased or alive) from any hospital center with a confirmed diagnosis or a COVID-19 high suspicion.
排除标准
- •There are no exclusion criteria, except for the patient's explicit refusal to participate.
结局指标
主要结局
Death
时间窗: through study completion, an average of 1 month
All cause
次要结局
- In hospital stay.(through study completion, an average of 1 month)
- Heart failure(through study completion, an average of 1 month)
- Renal failure(through study completion, an average of 1 month)
- Respiratory Insufficiency.(through study completion, an average of 1 month)
- Upper respiratory tract involvement(through study completion, an average of 1 month)
- Pneumonia(through study completion, an average of 1 month)
- Sepsis(through study completion, an average of 1 month)
- Clinically relevant bleeding(through study completion, an average of 1 month)
- Systemic inflammatory response Syndrome.(through study completion, an average of 1 month)
- Other complications.(through study completion, an average of 1 month)
研究者
IVAN J NUÑEZ GIL
Principal Investigator. Attending Physician. MD, PhD, FESC
St Carlos Hospital, Madrid, Spain