Extended Application of Intraoperative Parathyroid Scores System(IPSS) in Thyroidectomy
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Differences of parathyroid records between IPSS and TD
研究概览
简要总结
after established the Intraoperative Parathyroid Scores System (IPSS) for thyroidectomy we further extented the clinical value of Intraoperative Parathyroid Scores System in Treatment decisions of calcium treatment time and improve recognition skills of parathyroid in Clinicians
详细描述
IPSS includes transplantation Parathyroid Scores and in situ Parathyroid Scores, the investigators will establish the Intraoperative Parathyroid Scores System by parathyroid size and Blood supply, and recording IPSS, according to certain rules. We expand IPSS, including the description of the location of parathyroid after postoperative.Parathyroid hormone and calcium were test in d0, d1, d14, d60 post operation. The correlation between Intraoperative Parathyroid Scores and PTH calcium were calculated, and ROC curve and logistic regression were tested for the prediction value.and after that we further evaluate the relationship Between IPSS and calcium supplement time.and Whether IPSS enhance ability of parathyroid recognition for clinical doctors.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •postoperative pathology confirmed as thyroid papillary carcinoma;
- •for the first time to undergo thyroid surgery, no history of neck surgery and external radiotherapy;
- •preoperative serum calcium, parathyroid hormone levels were normal;
- •intraoperative and postoperative clinical data integrity, standardized follow-up patients;
- •parathyroid is a tumor violation.
排除标准
- •serious underlying disease;
- •age greater than 60 years of age or combined with arteriosclerotic disease;
- •patients with postoperative loss;
- •patients with parathyroid disease.
结局指标
主要结局
Differences of parathyroid records between IPSS and TD
时间窗: 1 year
The percentage of recorded integrity of the parathyroid gland and the number of recognizable parathyroids were compared between the two groups.
次要结局
- The effect of IPSS on the level of parathyroid recognition of surgeons(1 year)
- differences of the number of parathyroid glands found in the pathology betwen IPSS and TD(1 year)
研究者
Bo Wang,MD
MS
Fujian Medical University