Effects of Computer-aided Interlimb Force Coupling Training on Paretic Hand and Arm Motor Control Following Chronic Stroke
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Upper Extremity motor control of Fugl-Meyer Assessment (FMA-UE)
研究概览
简要总结
The investigators hypothesized that bilateral handgrip force training would result in significant improvements in paretic hand, arm movements and daily functional performances. In order to investigate whether the improvement of paretic hand could facilitate the motor recovery of paretic arm and functional performances, the investigators also hypothesized that motor recovery and functional performances improvements of paretic arm and hand have strongly correlation.
详细描述
Objective: To investigate the training effects of interlimb force coupling training on paretic hand and upper extremity outcomes in patients with chronic stroke; to analyze the relationship between motor recovery of paretic hand, arm and functional abilities.
Design: A double-blind randomized controlled trial with outcome assessment at baseline and after 4 weeks intervention.
Setting: Department of physical medicine and rehabilitation in Taipei Veterans General Hospital.
Participants: Thirty-three subjects (mean age = 55.1 ± 10.5 y/o) with chronic stroke were recruited and randomized assigned to training (n=16) and control group (n=17).
Interventions: Interlimb force coupling training task included different gripforce generation on the both hands.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 28 Years 至 81 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •at least 6 months since stroke
- •three or fewer incidents of unilateral stroke confirmed by taking the participant's medical history ability to follow researcher's instructions
- •ability to flex and extend the paretic arm and hand
- •Modified Ashworth Score (MAS) ≦3 for wrist and finger joints
- •Mini-Mental State Examination (MMSE) score should 24 or higher
- •no other orthopedic neurological disorders
- •Brunnstrom stage 3 or 4
- •no joint in other experimental rehabilitation or drug studies 21
排除标准
- •unstable cardiovascular conditions
- •uncontrolled hypertension (190/110 mm Hg)
- •severe orthopedic or pain conditions
- •dementia (Mini-Mental State Examination score < 22)
- •aphasia with inability to follow researcher's commands
- •severe joint contracture of bilateral upper extremities that would impact the movement performances of upper extremities
研究组 & 干预措施
Education & training consultation
Education and training consultations were provided for subjects in control group during study period.
干预措施: Bilateral movement training (Procedure)
Bilateral movement training
Exercise training of bilateral isometric handgrip force training group consisted of 60 minutes of bilateral isometric handgrip force training 3 days per week for 4 weeks (total 12 sessions)
干预措施: Bilateral movement training (Procedure)
结局指标
主要结局
Upper Extremity motor control of Fugl-Meyer Assessment (FMA-UE)
时间窗: before and after 4 weeks intervention
Outcome measure was assessed before and after 4 weeks intervention.
次要结局
- Barthel Index (BI)(before and after 4 weeks intervention)
- Wolf Motor Function Test (WMFT)(before and after 4 weeks intervention)
- Motor Assessment Score (MAS)(before and after 4 weeks intervention)
研究者
Chueh-Ho Lin
Dr.
National Yang Ming Chiao Tung University