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临床试验/NCT05353413
NCT05353413Unknown不适用

Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.

Medical University of Bialystok2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2020年1月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
20
试验地点
2
主要终点
sigma parameter

研究概览

简要总结

The aim of the project is to create a new, non-invasive and safe protocol for the early diagnosis of various types of optic neuropathies with the use of diffusion magnetic resonance imaging

详细描述

In this study, it is planned to find twenty volunteers for each of the neuropathies and twenty healthy volunteers. Each volunteer will undergo clinical tests such as visual acuity, color vision, intraocular pressure measurement, assessment of the anterior chamber and fundus using a slit lamp and Volk lens, macular optical coherence tomography examination and examination of the optic nerve disc (OCT), neurological field vision and visual evoked potential (VEP) testing. Each of the volunteers will undergo magnetic resonance imaging. During active scanning, patients will be asked for not blinking or moving their heads by staring at the red dot on the outside of the camera reflected in the coil mirror. The obtained diffusion tensor data will be used for further analysis.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Diagnostic
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Optic neuropathy.

排除标准

  • common contraindications to MRI (presence of pacemaker, non-MRI-safety or claustrophobia)

结局指标

主要结局

sigma parameter

时间窗: one month

sigma parameter in our algorithm provides a quantitative measure of nerve atrophy

次要结局

未报告次要终点

研究者

发起方
Medical University of Bialystok
申办方类型
Other
责任方
Sponsor

研究点 (2)

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