Treatment for Hidradenitis Suppurativa
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 1
- 主要终点
- Therapeutic Effect of Methalazine on 27 Cases of Suppurative Hidradenitis
研究概览
简要总结
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory relapsing disease involving the axillae, breast ,groin and anogenital regions. The therapies of the disease are diverse, including medication and surgery. However, responses to treatments are variable and relapse is common, with no single agent being consistently effective.
Objective: To evaluate the efficacy and safety of oral mesalazine treatment for hidradenitis suppurativa .
Methods: Investigators reported a series of cases of patients who received oral mesalazine(1g qid) for hidradenitis suppurativa in our institution between May 2020 and September 2023. A total of 27 patients, 22 in the mild to moderate group and 5 in the severe group, were included in this study.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Recurrent painful or suppurative lesions
- •Typical clinical manifestations: the distribution of apocrine sweat glands is deep in painful nodules, abscesses, sinuses, scars;
排除标准
- •Severe neurological and psychiatric diseases
- •Tumor diseases
- •Pregnant women in lactation period
结局指标
主要结局
Therapeutic Effect of Methalazine on 27 Cases of Suppurative Hidradenitis
时间窗: Three and a half years
We registered the number of patients who achieved HiSCR（%）.
次要结局
未报告次要终点
研究者
Hou Maihua
Chief physician
The First Affiliated Hospital with Nanjing Medical University