NCT04369014Unknown不适用
Characteristic Changes During Anesthesia With Etomidate and Propofol
Air Force Military Medical University, China1 个研究点 分布在 1 个国家目标入组 68 人开始时间: 2022年2月28日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- delta wave deficiency during anesthesia
研究概览
简要总结
Electroencephalography (EEG) monitoring reflect the brain electro-activity. Different anesthetics may show different changes in EEG during anesthesia. Etomidate and propofol are widely used for general anesthesia. The characteristic changes of these two anesthetics may be different.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for surgery under general anesthesia
- •Patients provided written informed consent
排除标准
- •Patients with history of neurological or psychiatric diseases
- •Patients younger than 18 years old
- •Patients scheduled for surgery involved head
- •Patients with pregnancy or planned for breeding
研究组 & 干预措施
etomidate
Experimental
干预措施: etomidate anesthesia (Drug)
propofol
Experimental
干预措施: propofol anesthesia (Drug)
结局指标
主要结局
delta wave deficiency during anesthesia
时间窗: from anesthesia induction to extubation of the endotracheal tube, on an average of 2.5 hours
次要结局
- spindle wave deficiency during anesthesia(from anesthesia induction to extubation of the endotracheal tube, on an average of 2.5 hours)
- burst suppression during anesthesia(from anesthesia induction to extubation of the endotracheal tube, on an average of 2.5 hours)
研究者
Zhihong LU
Professor
Air Force Military Medical University, China
研究点 (1)
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