NCT04234139Enrolling By Invitation不适用
Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver Transplantation
适应症
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Number of participants who survived within 1 year post-transplant
研究概览
简要总结
The purpose of this study is to develop a clinical understanding of early liver transplantation (ELT) for patients with severe alcoholic hepatitis (SAH) and identify the public's opinion regarding this practice.
详细描述
The research study is designed to improve the investigators' understanding of early liver transplantation for patients with severe alcoholic hepatitis. The goal of this research is twofold:
- Establish a knowledge base necessary for appropriate liver transplant candidate selection by quantifying post-ELT mortality for SAH and compare to outcomes to liver transplantation for other indications
- Develop an ethical framework for implementation of these transplants for SAH based on the opinions of healthcare providers and the general public.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Number of participants who survived within 1 year post-transplant
时间窗: 1 years
Post-transplant survival within one year of the surgical procedure.
次要结局
- Number of participants who self-report or have biochemically measured alcohol recidivism or relapse within 1 year post-transplant(1 years)
研究者
研究点 (1)
Loading locations...
相似试验
招募中
不适用
ADDICTOlogical Intervention in LIVEr Transplantation RecipientsAlcohol Associated Liver DiseaseLiver TransplantationNCT06472973University Hospital, Montpellier720
招募中
不适用
Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAHAlcohol Use DisorderAlcoholic HepatitisNCT03845205Johns Hopkins University200
招募中
不适用
Functional Assessment in Liver TransplantationEnd Stage Liver DiseaseNCT03228290University of California, San Francisco5,000
已完成
3 期
CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal ImpairmentEnd Stage Liver DiseaseImpaired Renal FunctionNCT00604357University of Regensburg27
招募中
不适用
The ImmunoXXL StudyHepatocellular CarcinomaNCT05879328Fondazione IRCCS Istituto Nazionale dei Tumori, Milano12
