JPRN-UMIN000016683已完成1 期
ovel autologous dendritic cell vaccine therapy targeting HTLV-1 specific antigen Combined with anti-CCR4 antibody for previously treated patients with adult T-cell leukemia. A phase Ia/Ib study. - Phase Ia/Ib study of Tax-targeting DC vaccine combined with anti-CCR4 Ab for AT
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 9
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 75years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) Patients with severe complications: cardiovascular disorders, respiratory disorders, renal dysfunction, immunodeficiency, hematological disorders, autoimmune diseases, sever allergy and severe infectious disease. 2) Patients who should receive systemic administration of steroid or immunosuppressive agents. 3) Non-hematological adverse event Grade 3 or more due to KW-0761 before the trial are not recover 4) After allogeneic hematopoietic stem cell transplantation, or allograft is planned 5) Presence of active central nerve lesion 6) Pregnant, lactating, or possibly pregnant women, or willing to be pregnant Severe psychiatric disorder 7) Complication with psychosis or psychotic symptoms 8) History of HAM/TSP 9) Active multiple cancers 10) Inappropriate for study entry judged by an attending physician
研究者
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