NCT01410838已完成不适用
Effects of Ingesting Monosodium Glutamate (MSG) on Energy Balance and Eating Behavior Following Moderate Energy Restriction and Weight Loss in Overweight Women
USDA, Western Human Nutrition Research Center2 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2011年8月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 44
- 试验地点
- 2
- 主要终点
- Change in body weight
研究概览
简要总结
This study will test whether regular consumption of Monosodium Glutamate (MSG) immediately prior to each of the three major meals (breakfast, lunch, dinner) inhibits body weight and fat regain following a period of moderate, yet clinically significant weight loss.
详细描述
The proposed study enables us to assess the long term effects of consuming MSG on body weight regain following weight loss.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 19 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age 19-45
- •BMI 27-35
- •Blood pressure <140/90
- •Non-smoking
排除标准
- •Anemic: hgb < 11.5 mg/dL
- •Sensitivity to MSG (self reported)
- •Pregnant or planning to get pregnant
- •Taking medication for hypertension, depression, or weight loss
- •Vegetarian
- •MRI Contraindications: internal metal, braces on teeth, history of metal in the eye, claustrophobia
- •blindness or heavily corrected vision
- •not fluent in English
结局指标
主要结局
Change in body weight
时间窗: weeks 11, 12, and 25
Subjects will have their body weight measured to determine the effect of MSG on body weight regain following weight loss.
次要结局
- Change in eating behavior(weeks 11, 12 and 25)
- Change in body fat(weeks 11 and 25)
- Change in resting energy expenditure(weeks 11, 12, and 25)
研究者
研究点 (2)
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