NCT00100958已完成1 期
Phase I Ascending Single Dose Pharmacokinetics (PK) and Safety Study of 3,3' Di-Indolymethane (DIM) Nutritional Product
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 试验地点
- 2
研究概览
简要总结
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of indole-3-carbinol may prevent cancer.
PURPOSE: This randomized phase I trial is studying the side effects and best dose of indole-3-carbinol and to see how well it works compared to placebo in preventing cancer in healthy participants.
详细描述
OBJECTIVES:
Primary
- Determine the maximum tolerated dose of indole-3-carbinol in healthy participants.
- Determine the safety and tolerability of this drug in these participants.
- Determine the pharmacokinetics of this drug in these participants.
Secondary
- Determine the effects of this drug on selected markers of sexual function in these participants.
- Determine the effects of this drug on markers of susceptibility to cancer in these participants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 主要目的
- Prevention
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究者
研究点 (2)
Loading locations...
相似试验
已完成
1 期
UMCC 2003-064 Resveratrol in Preventing Cancer in Healthy ParticipantsUnspecified Adult Solid Tumor, Protocol SpecificNCT00098969National Cancer Institute (NCI)40
已完成
1 期
Nitric Oxide-Releasing Acetylsalicyclic Acid in Preventing Colorectal Cancer in Patients at High Risk of Colorectal CancerColorectal CancerNCT00331786Stony Brook University240
已完成
1 期
Lycopene in Preventing Prostate Cancer in Healthy ParticipantsProstate CancerNCT00093561University of Illinois at Chicago
已完成
1 期
Lycopene in Preventing Prostate Cancer in Patients Who Are at High Risk of Developing Prostate CancerProstate CancerNCT00416325University of Illinois at Chicago18
已完成
1 期
Oltipraz in the Prevention of Lung Cancer in People Who SmokeLung CancerNCT00006457Northwestern University