Structural Cartography of the Insula in Temporal Epilepsy Patients
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 115
- 试验地点
- 1
- 主要终点
- cartography of insula in temporal epilepsy patients
研究概览
简要总结
The purpose of this study is to investigate insula structural connectivity in temporal epilepsy patients. Insula being at the interface of frontal, parietal, occipital and temporal lobes, its structural organization reflects the brain function. We hypothetize that insular structural organization will be different according to the different subtypes of temporal epilepsy.
详细描述
The purpose of this study is to investigate insula structural connectivity in temporal epilepsy patients. Insula being at the interface of frontal, parietal, occipital and temporal lobes, its structural organization reflects the brain function. We hypothetize that insular structural organization will be different according to the different subtypes of temporal epilepsy.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •epileptic patients: temporal epilepsy or temporal plus epilepsy (temporomesial epilepsy, basal temporal epilepsy, mesio lateral or lateral epilepsy, temporo insular epilepsy, operculo insular epilepsy)
- •patients who underwent video EEG monitoring with recorded seizures (at least one)
- •patients who underwent a brain MRI with DTI sequence before epilepsy surgery
- •patients who did not refuse the use of their clinical and MRI data for this study
排除标准
- •patients younger than 15 years old
- •patients with previous brain surgery (before MRI)
- •uncompleted MRI sequences (DTI, T1 anatomical)
结局指标
主要结局
cartography of insula in temporal epilepsy patients
时间窗: 1 year after the last inclusion
Compared with healthy group, definition of different patterns of insular structural connectivity in epileptic patients
次要结局
- Correlation structural cartography and electroclinical data(1 year after the last inclusion)
研究者
TYVAERT Louise
Principal Investigator
Central Hospital, Nancy, France