ISRCTN75653261已完成未知
Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia
German CLL Study Group (GCLLSG)0 个研究点目标入组 375 人开始时间: 2005年4月26日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 375
研究概览
简要总结
- 2006 results in https://www.ncbi.nlm.nih.gov/pubmed/16219797 (added 25/01/2019) 2. 2007 results in https://www.ncbi.nlm.nih.gov/pubmed/17389338 (added 25/01/2019)
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Patients with an age of up to 65 years with untreated CLL in advanced stage (all Binet stage C patients; Binet stage B with symptoms, which require therapy; Binet stage A with severe B-symptoms).
排除标准
- •Patients with an age less than 18 and more than 65 years were excluded as well as patients with any previous treatment of CLL, life expectancy less than six months and an Eastern Cooperative Oncology Group performance status of more than two. Patients were also excluded if they had severe organ dysfunction, concomitant or previous other neoplasms or
- •an autoimmune hemolytic anemia or thrombocytopenia.
研究者
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