NCT01425411已完成4 期
Effect of Valsartan on Left Ventricular Myocardial Functions in Hypertensive Patients With Left Ventricular Hypertrophy
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- change from baseline in midwall fractional shortening (mFS) and tissue Doppler systolic wave (Sm) measured by echocardiography at six months
研究概览
简要总结
The study hypothesis: Valsartan as an angiotensin II receptor blocker treatment has beneficial effects on both midwall mechanics and myocardial functions in hypertensive patients with Left ventricular hypertrophy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •hypertension with left ventricular hypertrophy
排除标准
- •clinical or laboratory evidence of secondary hypertension
- •heart failure
- •ischemic heart disease
- •valvular heart disease
- •arrhythmias
- •peripheral vascular disease
- •chronic obstructive pulmonary disease
- •neurologic disorders
- •diabetes mellitus
- •renal dysfunction
- •notable systemic disease
研究组 & 干预措施
Valsartan treatment
Experimental
干预措施: valsartan (Drug)
结局指标
主要结局
change from baseline in midwall fractional shortening (mFS) and tissue Doppler systolic wave (Sm) measured by echocardiography at six months
时间窗: six months
次要结局
- change from baseline in systolic and diastolic blood pressure at six months(six months)
- change from baseline in left ventricular mass index measured by echocardiography at six months(six months)
研究者
Nagehan Kucukler
MD
Mustafa Kemal University
研究点 (1)
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