NCT00610064已完成不适用
Brain Effects of Sacral Neuromodulation in Patients With Refractory Lower Urinary Tract Dysfunction
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Effect of sacral neuromodulation on brain activity
研究概览
简要总结
Sacral neuromodulation (SNM) has become an accepted treatment for patients with refractory lower urinary tract dysfunction such as urgency frequency syndrome, urgency incontinence, non-obstructive chronic urinary retention and chronic pelvic pain syndrome. Modulation of central afferent activity is considered critical to this therapeutic effect but the neural mechanisms are poorly understood.
We hypothesize that SNM has a significant effect on brain activity detectable by positron emission tomography (PET).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with refractory lower urinary tract dysfunction scheduled for sacral neuromodulation
排除标准
- •Pregnancy
- •Age <18 years
- •Claustrophobia
结局指标
主要结局
Effect of sacral neuromodulation on brain activity
时间窗: 2-8 weeks
次要结局
- Differences in brain activity effects of sacral neuromodulation (SNM) in patients with successful compared to failed SNM testing(immediately and 2-8 weeks after study inclusion)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Secondary Bilateral Sacral Nerve Stimulation in Overactive Bladder PatientsBladder HyperactivityNCT01960270University Hospital, Rouen34
招募中
不适用
Sacral Neuromodulation for Chronic Pelvic PainChronic Pelvic Pain SyndromeNCT06150599Corewell Health East25
尚未招募
不适用
The influence of sacral neuromodulation on brain areas involved in the sensation of bladder filling in patients with Overactive Bladder (OAB) using fMRINL-OMON56105Medisch Universitair Ziekenhuis Maastricht95
已完成
不适用
Sacral Neuromodulation for Neurogenic LUT DysfunctionRefractory Neurogenic LUTDNCT02165774University of Zurich61
终止
不适用
The Effects of Sacral Neuromodulation for Urinary Urgency, Frequency, and Urge IncontinenceUrinary Urge IncontinenceNCT02776475TriHealth Inc.18