NCT05716867进行中（未招募）不适用
The Evidence of Early Childhood Caries Prediction by Salivary Cystatin S Levels in a Group of Egyptian Children: a Case Control Study
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Levels of salivary cystatin S protein
研究概览
简要总结
Aim of the study
- Measuring the levels of salivary cystatin S protein and salivary buffering capacity to determine their relation to early childhood caries.
- Predection of early childhood caries by using salivary cystatin S levels with demographic, clinical and nutrition habits characteristics of the participants.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 36 Months 至 71 Months（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Medically free children aged 36 to 71 months with one or more decayed (noncavitated or cavitated lesions), missing, or filled teeth due to caries in any primary tooth(cases).
- •Medically free children aged 36 to 71 months with no decayed, missing, or filled teeth due to caries in any primary tooth(controls).
排除标准
- •Children receiving antibiotic therapy within three month and fluoride prophylaxis within one year.
- •Parents who will refuse to participate or refuse to sign the informed consent.
- •Children who will not agree or cooperate with participation.
研究组 & 干预措施
Children with early childhood caries aged between 36-71 month
干预措施: Measurement of salivary cystatin S protein levels in saliva (Biological)
Caries free children aged between 36-71 month
干预措施: Measurement of salivary cystatin S protein levels in saliva (Biological)
结局指标
主要结局
Levels of salivary cystatin S protein
时间窗: 2 months
Levels of salivary cystatin S protein measured by Human cystatin S enzyme linked immunosorbent assay (ELISA) kit (unit ng/ml)
次要结局
- Buffer Capacity(2 months)
- Demographic, clinical and nutrition habits characteristics of participants Interview(2 months)
研究者
Tasneem Salah Sayed Mohamed Abo Ali
principle investigator
Cairo University
研究点 (1)
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