Enhanced Deep Learning Model for Diagnosis of Pancreatic Solid Lesions Through Multimodal Clinical Images
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Researchers use artificial intelligence (AI) support system to assist in diagnosis of pancreatic solid space-occupying lesions
研究概览
简要总结
Solid lesions of the pancreas mainly include tumor and non tumor lesions. More than 90% of pancreatic tumor lesions are pancreatic cancer, which is characterized by high mortality and poor prognosis and requires surgical treatment; Non-tumor lesions of the pancreas are mainly inflammatory lesions, which usually do not require surgical treatment, but can be treated with drugs. The common ones are chronic pancreatitis and autoimmune pancreatitis, with a good prognosis. Clinically, the differential diagnosis between them is very difficult. Multi-disciplinary diagnosis and treatment of MDT makes our understanding of pancreatic diseases increasingly rich and in-depth. From disease diagnosis to preoperative evaluation and curative effect evaluation, non-invasive imaging involves almost every link under MDT mode. In view of this, improving the differential diagnosis of pancreatic solid space-occupying lesions on imaging will be more conducive to the diagnosis and treatment under MDT mode, so new technologies such as artificial intelligence should be considered. Our goal is to develop a clinically applicable artificial intelligence system, which uses multiple modes to simulate the routine clinical workflow and assist in the diagnosis of benign and malignant pancreatic solid space-occupying lesions.
详细描述
The diagnosis of solid pancreatic lesions is challenging, MDT is a very effective method, but it has a certain misdiagnosis rate. This is a multi-center, prospective and observational clinical study. Our goal is to develop a clinically applicable artificial intelligence system. On the one hand, our artificial intelligence based on clinical data+CT imaging images can assist MDT doctors to diagnose the nature of pancreatic space-occupying lesions and reduce misdiagnosis; On the other hand, if a patient needs EUS-FNA puncture, the multimodal artificial intelligence system based on clinical data+CT+EUS developed by us can help MDT doctors understand the nature of pancreatic space-occupying lesions and reduce the probability of misdiagnosis or secondary puncture.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •pancreatic solid mass in CT and EUS
排除标准
- •insufficient imaging quality of CT or EUS
- •endoscopic ultrasound non accessible lesions
结局指标
主要结局
Researchers use artificial intelligence (AI) support system to assist in diagnosis of pancreatic solid space-occupying lesions
时间窗: 2 months
A multi-layer screening deep convolution network based on deep convolution network was developed to observe its accuracy, sensitivity and specificity in assisting MDT doctors to identify benign and malignant pancreatic space-occupying lesions.
次要结局
未报告次要终点
