Breast Cancer Bank of Tissue From Trial Assigning Individualized Options for Treatment (TAILORx Tissue Bank)
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 600
- 试验地点
- 12
- 主要终点
- Disease relapse, endocrine and/or chemotherapy resistance prognosis
研究概览
简要总结
This is an exploratory, translational, non-interventional and multi-centre biobank. The aim of the development of such a biobank is to identify potential biomarkers that are indicative of disease relapse.
详细描述
The primary objective is to develop a biobank, tissue microarrays (TMAs) and full face sections, which will be used to identify candidate/ novel biomarkers prognostic for disease relapse and predictive for endocrine and/or chemotherapy resistance.
The secondary objectives are:
- To validate emerging signatures/biomarkers identified.
- To develop new assays for the breast cancer clinic.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients that were registered with the ICORG 06-31 TAILORx trial and participated in trial arms
- •Patients with adequate tumor tissue available
排除标准
- 未提供
结局指标
主要结局
Disease relapse, endocrine and/or chemotherapy resistance prognosis
时间窗: For duration of follow up, expected 10 years
A biobank, TMAs and full face sections, will allow for the identification of candidate/novel biomarkers prognostic for disease relapse and predictive for endocrine and/or chemotherapy resistance
次要结局
- Signature/biomarkers(For the duration of follow up, expected 10 years)