Correlation Of Serum Intact Parathyroid Hormone and Serum Alkaline Phosphatase Amongst the Patients of Chronic Kidney Disease in A Rural Tertiary Care Hospital in Central India

a study conducted in a rural tertiary care hospital in Central India aiming to investigate the correlation between serum intact parathyroid hormone (iPTH) and serum alkaline phosphatase (ALP) levels among patients with Chronic Kidney Disease (CKD). The rationale behind the study is to assess cost-effective investigations for diagnosing CKD mineral and bone disorder (MBD) and potentially improving patient outcomes. The study design is a cross-sectional study with a duration of 24 months, conducted at Acharya Vinoba Bhave Rural Hospital. The sample size is determined to be 120 patients meeting specific inclusion criteria. Data collection involves obtaining baseline demographic and clinical data, including age, gender, BMI, and blood pressure, and analyzing serum samples for various biochemical markers. Ethical considerations, including patient confidentiality and informed consent, are emphasized. The primary outcome is the correlation between iPTH and ALP levels, while secondary outcomes include assessing MBD prevalence, disease burden across CKD stages, and exploring factors associated with elevated iPTH and ALP levels. The abstract highlights the study’s potential contributions to CKD management in the rural Indian population.