Clinical Evaluation of Maha Triphaladya Ghrita in the Management of Dry Eye Syndrome (Shushkakshipaka). - IMCRP- DES-2010-2011

Central Council for Research in Ayurvedic Sciences CCRAS0 个研究点目标入组 150 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1. Patients presenting with signs and symptoms of Dry eye syndrome.
•Schirmer-I test positive i.e.Ã? < 10 mm.
•Tear film break-up time less than 10 seconds.Ã?
•Rose Bengal staining showing devitalized epithelium of conjunctiva and mucus plaques on the cornea.Ã?
•(If Any two of the above three criteria are present; the diagnosis of Dry Eye Syndrome is confirmed)
•2. Willing and able to participate in the study for 16 weeks.

•1. Severe cases of dry eye syndrome with complications like perforated corneal ulcer, Uveitis, Glaucoma.
•2. Inflammatory conditions like acute conjunctivitis etc.
•3. Systemic diseases causing Dry Eye Syndrome.
•4. Patients with concurrent serious Hepatic Dysfunction (defined as AST and/or ALT > 2 times of the upper normal limit) or Renal Dysfunction (defined as S. creatinine > 1.2mg/dl), uncontrolled Pulmonary Dysfunction (asthmatic and COPD patients) or other concurrent severe disease.
•5. Patients with poorly controlled Diabetes Mellitus (HbA1c > 10%)
•6. Women who are pregnant or lactating
•7. Patients on steroids, oral contraceptive pills, estrogen replacement therapy or any other medication that may adversely affect the outcome of the study
•8. Smokers/Alcoholics and/or drug abusers
•9. Patients with poorly controlled Hypertension ( >160/100 mm of Hg)
•10. Patients with evidence of malignancy
•11. Patients suffering from major systemic illness necessitating long term drug treatment (Rheumatoid arthritis, Psycho-Neuro- Endocrinal disorders, etc.)
•12. H/o hypersensitivity to the trial drug or any of its ingredients.
•13. Patients who have completed participation in any other clinical trial during the past six (06) months.
•14. Any other condition which the Principal Investigator thinks may jeopardize the study.

发起方

Central Council for Research in Ayurvedic Sciences CCRAS