The Chinese Population Health and Multimorbidity Study: Baseline Survey, and Follow-up Investigation
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 50,991
- 试验地点
- 1
- 主要终点
- Occurrence of multimorbidities
研究概览
简要总结
The Chinese Population Health and Multimorbidity Study (CPHMS; initially named China Pulmonary Health Study, CPHS) was a large-scale epidemiological survey designed to investigate the pulmonary health of Chinese adults aged 20 years or older leveraging a multistage stratified sampling scheme between 2011 and 2014 in mainland China. Briefly, a total number of 57,779 local residents were recruited from 10 representative provinces and municipalities and were invited to participate in the study. A final number of 50,991 adults who met the major inclusion criteria could be considered in further analyses.
In order to investigate the changes of pulmonary health and disease status (e.g. occurrence and development of chronic respiratory diseases and other important relevant multimorbidities, lung function indices, etc.) and corresponding impact factors in the CPHMS study population, we plan to initiate the first round of follow-up investigation between 2025 and 2027 (planned) , i.e. more than 10 years after the baseline survey.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •(1) the individuals who participated in the CPHMS baseline survey;
- •(2) their ID number and phone number are available;
- •(3) sign the informed consent.
排除标准
- •(1) incapable of taking pre- and post-bronchodilator spirometry tests;
- •(2) request to withdraw the informed consent;
- •(3) terminate due to medical or ethical considerations judged by the investigators and/or ethics committee.
结局指标
主要结局
Occurrence of multimorbidities
时间窗: Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS)
Occurrence of chronic respiratory diseases, cardiovascular and cerebrovascular diseases, malignant tumors, and/or metabolic diseases, etc.
次要结局
- Changes of lung function, forced expiratory volume in one second (FEV1)(Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS))
- Changes of lung function, forced vital capacity (FVC)(Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS))
- Changes of lung function, FEV1/FVC(Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS))
- Changes of lung function, the percentage of measured FEV1 value to the predicted value (FEV1%pred)(Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS))
研究者
Jieping LEI, Ph.D.
Ph.D.
China-Japan Friendship Hospital