Does Antibiotic Prophylaxis at Urinary Catheter Removal Prevent Urinary Tract Infections
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- UTI
研究概览
简要总结
At the end of most urological procedures, the doctor inserts a urethral catheter for a period of up to 5 days. According to AUA's guidelines, prophylactic antibiotic is indicated during catheter removal.
The aim of our study is to check the influence of the antibiotic treatment on urinary tract infections after catheter removal
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •performing urological operation for other reason
排除标准
- •cannot give informed consent
- •<18 years
研究组 & 干预措施
Antibiotic prophylaxis
Single dose of p.o. antibiotic given 1 hour before catheter removal. The antibiotic of choice is Cefuroxime axetil 500 mg. For penicillin allergy, trimethoprim/sulfamethoxazole 160mg/800mg.
干预措施: Cefuroxime axetil (trimethoprim/sulfamethoxazole if penicillin allergy) (Drug)
结局指标
主要结局
UTI
时间窗: 30 day
Number of participants with primary care/emergency department visits because of dysuria, fever, chills or other UTI related symptoms
次要结局
- Hospitalizations due to UTI(30 day)
- Bacteremia(30 day)
- positive culture approved UTI(30 day)
研究者
Omri Schwarztuch Gildor
Principal Investigator
Clalit Health Services