To compare analgesic efficacy of bilateral Quadratus Lumborum block vs Transversus Abdominis Plane block in patients undergoing laparoscopic Trans-abdominal Pre-peritoneal repair of inguinal hernia: a randomised control trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To assess the intraoperative and post-operative Fentanyl consumption over 24 hours of surgery
研究概览
简要总结
After completion of the study, we found that patients in QL group had lesser perioperative fentanyl requirements and longer lasting analgesia as compared to patients in TAP group. Post operative pain scores and comparison of quality of life assessed by QOR-SF-36 at 3 months post operatively were comparable. thus, we concluded that QL block was better in terms of perioperative analgesia in patents undergoing laparoscopic TAPP repair of inguinal hernia. There was no observable adverse effect to preclude the study. The study was printed in the form of thesis dissertation in June 2019 and accepted by AIIMS ethical board before final MD examination.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1 and 2, both unilateral and bilateral inguinal hernia.
排除标准
- •refusal to consent, BMI>35 kg/m2, history of allergy to local anesthetic, history of neurological or psychiatric disorder, active infection at the site of injection, bleeding diathesis-platelet count<100,00/mm3 and/or INR>1.5, patients unable to comprehend use of PCA pump, patients with recurrent or complicated hernia.
结局指标
主要结局
To assess the intraoperative and post-operative Fentanyl consumption over 24 hours of surgery
时间窗: 24 hours post-operatively
次要结局
- assessment of dermatomal coverage by 3 point scale(upto 30 minutes)
- calculate total performance time in each group(during blocks)
- observation of lower limb weakness(24 hours)
- time to first analgesic requirement indicated by the time when patient presses PCA button(immediate post operative period)
- comparison of NRS score between the two group(after awakenig,1hr, 2hr, 4 hr, 6hr,12 hr, 24 hr)
- quality of recovery at 24 hours by QoR-40 questionnaire(24 hours)
- quality of life assessment by SF-36 questionnaire(3 months post-operatively)
- incidence of post-operative nausea and vomitting(24 hours)