Brain Substrates for Cardiovascular Stress Physiology
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Oxygen consumption in response to acute psychological stress
研究概览
简要总结
Transcranial infrared laser stimulation is a non-invasive neuromodulation technique. The study will examine the effect of transcranial infrared laser stimulation on cardiovascular and metabolic responses to stress.
详细描述
Physiological responses to stress may be a potential pathway by which psychological stress relates to cardiovascular disease. Disproportionate (metabolically exaggerated) stressor-evoked cardiovascular reactions may accelerate atherosclerosis or influence risk of greater cardiovascular disease endpoints. The aim of this project is to use an experimental approach to examine if neuromodulation (transcranial infrared laser stimulation) alters stressor-evoked metabolic and cardiovascular responses.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-30 years old
排除标准
- •History of a diagnosed chronic medical or neurological disorder Current pregnancy Current illness or infection (e.g., cold, flu) Any condition that would prohibit them from engaging in physical exercise
结局指标
主要结局
Oxygen consumption in response to acute psychological stress
时间窗: Immediately following intervention (up to 60 minutes)
This measurement takes into account oxygen consumption at baseline and during the stress task.
Additional heart rate in response to acute psychological stress
时间窗: Immediately following intervention (up to 60 minutes)
This measurement takes into account additional heart rate at baseline and during stress.
Heart rate in response to acute psychological stress
时间窗: Immediately following intervention (up to 60 minutes)
This measurement takes into account heart rate at baseline and during the stress task.
次要结局
- Perceived stress(Immediately following intervention (up to 60 minutes))
研究者
Annie Ginty
Assistant Professor
Baylor University