Texas Regional Excellence in Cancer (TREC) @Texas A&M University Cancer Prevention Registry and Repository
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 2,500
- 试验地点
- 1
- 主要终点
- Frequency and nature of ADRs on the Naranjo Scale Questionnaire
研究概览
简要总结
This study collects health and genetic information to implement cancer prevention and treatment strategies.
详细描述
This research will explore how genetics, diet, exercise, and jobs influence the risk of developing cancers that can be treated early. The goal is to find out if this knowledge can help doctors and health insurers improve their methods for preventing cancers that cannot be treated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years of age and older, and,
- •People participating in the Cancer Prevention and Research Institute of Texas (CPRIT) A coordinated cancer screening research program in Bryan and Navasota Family Medicine Clinics and,
- •People with COPD, liver disease, cervical intraepithelial neoplasia (CIN) lesions, having had a colonoscopy or a low dose computed tomography (LDCT) lung scan or cervical exam in the last 12 months or scheduled for one, and,
- •Able to give and comprehend the consent process, and,
- •Able to consent to donate blood and urine samples, genetic material through buccal swabs for future research, and,
- •Able to understand that their specimens, health record, and changes in health status will be followed for a five-year period and shared in deidentified form with the research community, and,
- •All sexes and gender identities.
排除标准
- •Declines to participate or interact with staff/share their medical status.
- •A diagnosis of Alzheimer's disease or related dementias in a medical record indicates a progressive, debilitating condition that impairs memory, thought processes, and functioning Individuals who are unable or unwilling to provide consent will be excluded
结局指标
主要结局
Frequency and nature of ADRs on the Naranjo Scale Questionnaire
时间窗: 5 years
Measure the frequency and nature of adverse drug reactions by obtaining a complete medical history and physical examination and validating the patient's current concomitant medication list during the office visit. Patient medical information would be input into the ActX platform, which functions as a computable EHR medical record analysis, evaluation of polypharmacy status, and monitoring of ADRs using the Naranjo Scale will be conducted for the duration of the study.
次要结局
- Self-reported Health status and any significant changes(5 years)