The Effect of Stretching Exercises on Vascular Function, Blood Flow, and Walking Function in Middle and Older Adults
试验速览
- 阶段
- 不适用
- 入组人数
- 48
- 试验地点
- 2
- 主要终点
- Ultrasound parameters-pulsatility index(2)
研究概览
简要总结
This study examines the relationship between circulation and walking speed after performing 8-week stretching exercises.
详细描述
This study examines the relationship between circulations and walking speeds. Most studies in the field of stretching exercises have only focused on improvements of endothelial functions in younger population; however, I aim to emphasize its effects on different populations, such as people with frailty, low physical activity level, weakness and postoperative status. Previous research has established that stretching exercises can improve walking function by modulations of musculoskeletal or neuromuscular system. The importance and originality of this study are that it explores the relationship between circulation and walking speed. Due to the inability to extrapolate outcomes; short-term effect of improved blood vessel function; the unclear mechanism of stretching exercises; and considering the different physical fitness groups, I design a home-based, low-dose, and anatomic chain-based stretching exercises to verify the possible mechanism and effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 20 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age between 20-85 years old
- •Follow instructions
- •Walk with/without assistive technology
排除标准
- •Unstable acute or chronic health conditions
- •Peripheral vascular diseases
- •Non-musculoskeletal problems that would limit stretching exercises
- •Participate in other exercise programs
结局指标
主要结局
Ultrasound parameters-pulsatility index(2)
时间窗: during intervention(4th week)
(pulsatility index, PI)
Ultrasound parameters-peak-systolic velocity(2)
时间窗: during intervention(4th week)
（peak-systolic velocity, PSV）
walking speed-preferred(1)
时间窗: pre-intervention(1st week)
Timed 10-Meter Walk Test (preferred)
Ultrasound parameters-peak-systolic velocity(1)
时间窗: pre-intervention(1st week)
（peak-systolic velocity, PSV)
Ultrasound parameters-pulsatility index(1)
时间窗: pre-intervention(1st week)
(pulsatility index, PI)
vascular functions-Stiffness index(2)
时间窗: during intervention(4th week)
(Stiffness index, SI，unit：m/s)
vascular functions-Reflective index(1)
时间窗: pre-intervention(1st week)
(Reflective index, RI，unit：％)
Ultrasound parameters-pulsatility index(3)
时间窗: post-intervention(8th week)
(pulsatility index, PI)
Ultrasound parameters-diameter(2)
时间窗: during intervention(4th week)
（diameter, D）
Ultrasound parameters-area(2)
时间窗: during intervention(4th week)
（area, A）
walking speed-preferred(2)
时间窗: during intervention(4th week)
Timed 10-Meter Walk Test (preferred)
walking speed-preferred(3)
时间窗: post-intervention(8th week)
Timed 10-Meter Walk Test (preferred)
walking speed-fast(3)
时间窗: post-intervention(8th week)
Timed 10-Meter Walk Test (fast)
Ultrasound parameters-end-diastolic velocity(3)
时间窗: post-intervention(8th week)
（end-diastolic velocity, EDV）
Ultrasound parameters-mean velocity(3)
时间窗: post-intervention(8th week)
（mean velocity, mV）
Ultrasound parameters-mean volume flow(1)
时间窗: pre-intervention(1st week)
(mean volume flow, vFl)
Ultrasound parameters-mean volume flow(2)
时间窗: during intervention(4th week)
(mean volume flow, vFl)
Ultrasound parameters-mean volume flow(3)
时间窗: post-intervention(8th week)
(mean volume flow, vFl)
Ultrasound parameters-resistance index(1)
时间窗: pre-intervention(1st week)
(resistance index, RI)
vascular functions-Reflective index(3)
时间窗: post-intervention(8th week)
(Reflective index, RI，unit：％)
vascular functions-Vascular age
时间窗: pre-intervention(1st week)
(Vascular age, VA，unit：year-old)
Ultrasound parameters-mean velocity(1)
时间窗: pre-intervention(1st week)
（mean velocity, mV）
Ultrasound parameters-mean velocity(2)
时间窗: during intervention(4th week)
（mean velocity, mV）
Ultrasound parameters-resistance index(2)
时间窗: during intervention(4th week)
(resistance index, RI)
vascular functions-Stiffness index(1)
时间窗: pre-intervention(1st week)
(Stiffness index, SI，unit：m/s)
vascular functions-Stiffness index(3)
时间窗: post-intervention(8th week)
(Stiffness index, SI，unit：m/s)
vascular functions-Reflective index(2)
时间窗: during intervention(4th week)
(Reflective index, RI，unit：％)
Ultrasound parameters-end-diastolic velocity(1)
时间窗: pre-intervention(1st week)
（end-diastolic velocity, EDV）
Ultrasound parameters-resistance index(3)
时间窗: post-intervention(8th week)
(resistance index, RI)
Ultrasound parameters-area(1)
时间窗: pre-intervention(1st week)
（area, A）
Ultrasound parameters-peak-systolic velocity(3)
时间窗: post-intervention(8th week)
（peak-systolic velocity, PSV）
Ultrasound parameters-end-diastolic velocity(2)
时间窗: during intervention(4th week)
（end-diastolic velocity, EDV）
Ultrasound parameters-diameter(1)
时间窗: pre-intervention(1st week)
（diameter, D）
Ultrasound parameters-diameter(3)
时间窗: post-intervention(8th week)
（diameter, D）
Ultrasound parameters-area(3)
时间窗: post-intervention(8th week)
（area, A）
walking speed-fast(1)
时间窗: pre-intervention(1st week)
Timed 10-Meter Walk Test (fast)
walking speed-fast(2)
时间窗: during intervention(4th week)
Timed 10-Meter Walk Test (fast)
次要结局
- frailty(pre-intervention(1st week))
- body composition-weight(pre-intervention(1st week))
- body composition-waist circumference(pre-intervention(1st week))
- vital sign-blood pressure(1)(pre-intervention(1st week))
- vital sign-heart rate(3)(post-intervention(8th week))
- flexibility-chair sit and reach test (2)(during intervention(4th week))
- adherence of exercise(post-intervention(8th week))
- basic data(pre-intervention(1st week))
- body composition-height(pre-intervention(1st week))
- vital sign-blood pressure(2)(during intervention(4th week))
- flexibility-chair sit and reach test (1)(pre-intervention(1st week))
- grip strength(pre-intervention(1st week))
- cognitive function(pre-intervention(1st week))
- vital sign-blood pressure(3)(post-intervention(8th week))
- vital sign-heart rate(1)(pre-intervention(1st week))
- vital sign-heart rate(2)(during intervention(4th week))
- flexibility-chair sit and reach test (3)(post-intervention(8th week))
- ACSM-PAR-Q+(pre-intervention(1st week))
- IPAQ(pre-intervention(1st week))
- fitness(pre-intervention(1st week))
研究者
Mei-Wun Tsai
Associate Professor
National Yang Ming Chiao Tung University