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临床试验/NCT05200780
NCT05200780Unknown不适用

Standardization of Quantitative Muscle Ultrasonographic Parameters Among Egyptian Population

Assiut University0 个研究点目标入组 100 人开始时间: 2022年2月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
100
主要终点
get a refrence for ultrasonographic parameters muscle

研究概览

简要总结

1-standardization of semi quantitative muscle ultrasonographic parameters ( muscle thickness (MT) and echo intensity (EI) ) in healthy adults and to obtain a set of normal values of all accessible muscle in both upper and lower limbs.

2.standardizaition of quantitative muscle ultrasonographic parameters (Gray scale level (GSL), Calibrated muscle backscatter values (cMBs), Optical Density (OD), 2D Textu1) in healthy adults and to obtain a set of normal values of all accessible muscle in both upper and lower limbs.

详细描述

. Ultrasound is a widely used imaging technique in many different medical specialties. It is a non-invasive, safe and relatively cheap investigation method.

Ultrasound is a non-invasive method to quantitatively measure various muscle parameters.

Ultrasound imaging (US) has shown to be capable of visualizing normal and pathological skeletal muscles.(1) By measuring muscle thickness (MT) and echo intensity (EI) (=grey-value) of the muscle, structural changes caused by neuromuscular disorders can be detected. (2, 3, 4) Quantitative evaluation of US images is preferable over visual evaluation, because it is more sensitive and objective and offers the possibility to perform statistical analysis.(5) A prerequisite for the diagnostic use of quantitative muscle US is the availability of normal reference values.

Ultrasonography can detect structural muscle changes caused by neuromuscular disease. Quantitative analysis is the preferred method to determine if ultrasound findings are within normal limits, but normative data are incomplete.(6)

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
5 Years 至 70 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy subjects were recruited amongst colleagues and family members of the researchers
  • Age group (5-70)years
  • Male and female.

排除标准

  • Patient refuse to participate
  • The anatomy is altered due to sever trauma,tumor,or surgery

结局指标

主要结局

get a refrence for ultrasonographic parameters muscle

时间窗: 10 months

1. use new, easy ,non-invasive tool "neuromuscular ultrasound" 2. ultrasound give important morphological information of the muscles and can differentiate normal and diseased muscle. 1_use new, easy ,non-invasive tool "neuromuscular ultrasound" 2_ultrasound give important morphological information of the muscles and can differentiate normal and diseased muscle.1_use new, easy ,non-invasive tool "neuromuscular ultrasound" 2_ultrasound give important morphological information of the muscles and can differentiate normal and diseased muscle.

次要结局

  • detect early pathological changes in muscles(8 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Doaa Soliman Abd elhafeez

Standardization of quantitative muscle ultrasonographic parameters among Egyptian population

Assiut University

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